Medicinal chemistry – Page 7
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ResearchRisk of developing rheumatoid arthritis doubled by polycyclic aromatic hydrocarbons exposure
Study examined link between PAHs, phthalates, plasticisers and smoking and the condition
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WebinarBuilding organisational consensus around the tools of digital chemistry
Learn how change agents at Johnson Matthey developed a coalition of support for data-driven science
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NewsOverlooked documents shed new light on double helix discovery
Rosalind Franklin was more than just a ‘wronged heroine’
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NewsIndustry awaits decision on BPA as EU health bodies disagree on safe levels
European Food Safety Authority recommends 20,000-fold reduction in BPA levels
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BusinessMerck & Co to buy immunology specialist Prometheus
$10.8 billion cash deal give Merck rights to late-stage candidate for two inflammatory bowel conditions
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BusinessGhana and Nigeria approve Oxford malaria vaccine
Approval comes before final-stage clinical trials have been completed
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ResearchMechanochemically accelerated sublimations used to separate chiral molecules
New technique combines ball milling with NMR to monitor sublimations in real time
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NewsAfrica plans a network of genomics centres of excellence to tackle disease
Proposed $200 million programme to improve continent’s health would begin with two pilot centres
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ResearchSoapbark tree’s biosynthetic pathway for vaccine adjuvant saponins
Researchers use genome mining and bioengineering techniques to map out route
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NewsAir jet gun delivers needle-free vaccines in MOFs without any need for refrigeration
Release rate of injector system can be fine-tuned by changing the carrier gas
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OpinionThe toxic nature of yew, the tree of the dead
Historically associated with resurrection, yew is poisonous enough to kill
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ResearchGlow-in-the-dark proteins offer cheap and fast diagnostic tests
Covid-19 can be detected with the sensitivity of PCR and the ease of lateral flow
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BusinessPfizer to buy cancer biotech Seagen for $43 billion
Antibody-drug conjugate specialist will fill Pfizer’s cancer pipeline
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ResearchStudy challenges assumptions over how l-oligonucleotides behave in living systems
L-oligonucleotides are potentially cytotoxic but some could have unexpected therapeutic benefits
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ResearchPeptide tags that encode chemical libraries could revolutionise drug discovery
Simple strings of amino acids store over 4 gigabits of data, offering a highly stable solution for screening small molecule libraries
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ResearchSweetener erythritol linked to heart problems
Comprehensive study discovers high dietary intake of erythritol correlates with increased risk of heart attack similar to having diabetes
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ResearchDataset with millions of entries set to help AI find new drugs
Neural networks perform better when trained on larger datasets
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ResearchThe hunt is on for vaccine ingredients that don’t come from wild sharks
Yeast can provide the raw materials and chemical wizardry can transform them
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ResearchLipophilicity helps explain psychedelic drugs’ therapeutic effects
Understanding why psychedelic drugs that bind to serotonin receptors promote neuron growth, while serotonin itself does not