Medicinal chemistry – Page 9
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Research
Molecular trap that snares many different drugs could save lives during overdoses
Macrocyclic compound can mop up drugs of abuse in animal tests – including those for which no reversal agent exists
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Opinion
Setting drug development speed records
The pandemic treatment sprint was spectacular, but hard to match under less unusual circumstances
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Research
Benchtop machine automates synthesis of drug screening hits
System could boost the efficiencies of drug discovery campaigns
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Business
UK antibiotics supply chain stretched by surge in Strep A infections
Government enacts protocols to enable substitute treatments and recommends preventive prescriptions in severe cases
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News
Crispr moves into the clinic
A mere decade after its discovery Crispr is already in clinical trials for everything from sickle cell disease to HIV and cancer
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News
Europe’s largest, hi-tech life sciences building is planned for UK
With lab space in the UK in short supply, a British property firm and Dutch real estate developer are building a massive vertical campus in London
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Business
Pharmaceuticals roundup 2022
Following the huge success of vaccines and treatments for covid-19, companies are upping their investment in R&D and dealmaking
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Business
Theranos leaders to be imprisoned for blood testing fraud
Sunny Balwani and Elizabeth Holmes will both serve more than 10 years
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Research
Universal flu vaccine could head off future pandemics
More effective mRNA-based vaccine offers hope of ending annual flu shots for at risk groups
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Research
Surprise discovery as clam found to be producing complex antibiotic
Erythromycin was previously believed to be only synthesised by bacteria
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Research
Coca plants’ production pathway for cocaine finally unravelled
167-year-old biosynthetic mystery may be solved
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Research
Radium chelator researchers working to improve targeted cancer therapies
Oak Ridge National Lab team investigate factors underpinnning Ra2+ complex stability and selectivity in attempt to expand the therapeutic utility of radium-223
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Opinion
Embracing oddities
When new chemistry looks like alchemy or witchcraft, it’s worth taking notice
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Article
Thermal analysis in the development of long-acting injectable systems
Evaluating new polymers for slow-release drug delivery could deliver better treatment for patients
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News
World Health Organization takes aim at market as many still not getting vaccines they need
Government, industry and health organisations must do more
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Webinar
Analytical impurity standards – minimise project risk & avoid common pitfalls
Learn how to save time and money by understanding what’s at stake when working with analytical impurity standards.
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News
Alarm sounded after chemists discover new analogue of ketamine in Australia
Long-term health effects of novel psychoactive substance are unknown
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Research
Gut bacterium found to destroy nicotine offers liver health benefits for smokers
Discovery might lead to therapy for non-alcoholic fatty liver disease
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Article
Inspiring a new era of patient-centric medicines
Christian Jones discusses new formulations for drug delivery that put people first
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Research
Diverse pharmaceutical building blocks prepared with evolved enzymes
Computation guides enzyme evolution to produce high-value drug compounds