Molecular biology – Page 2
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ResearchAssembly theory puts chemistry centre stage to explain molecular complexity and life’s origins
Concept that attempts to join physics and biology via chemistry met with interest but also harsh criticism
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NewsmRNA vaccine pioneers win medicine Nobel prize
Katalin Karikó and Drew Weissman honoured for breakthroughs that enable the rapid development of new vaccines, including several of those used against Covid-19
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ResearchMapping antibiotic’s binding of its target points to way to give drugs the killer edge
Technique that creates a comprehensive catalogue of mutations in antibiotic’s target reveals how drugs might be improved
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ResearchRevived Neanderthal and Denisovan peptides show antibiotic activity
Molecular-scale ‘Jurassic Park’ process could uncover new medicines
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NewsScientists hope to illuminate unknown human proteins with new public database
‘Unknome’ database contains thousands of understudied proteins
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ResearchMolecular fossils solve evolutionary mystery
Fossilised protosteroids confirm Nobel-prizewinner’s decades-old prediction
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NewsBillionaire professor donates ‘transformative’ sum to protein science institute
$210 million endowment from entrepreneur and Moderna investor Tim Springer will support ongoing research
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ResearchAncient microbial natural products reconstructed from Neanderthal dental plaques
Palaeogenomic approach allows natural product researchers to ‘go back in time’
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NewsOverlooked documents shed new light on double helix discovery
Rosalind Franklin was more than just a ‘wronged heroine’
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NewsThe launch of a new field: precision microbiome editing
Nobel laureate Jennifer Doudna is helping lead a new $70 million project combining metagenomics and CRISPR to solve health, climate problems
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FeatureHow do plants sense stress?
How does an organism without a brain or a nervous system sense when it’s under attack? Hayley Bennett presents the plant world’s strange yet sophisticated system for responding to wounding
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ResearchOyster mushroom unleashes chemical warfare on its nematode prey
Fungus discovered to be using 3-octanone to paralyse and kill worms
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ResearchArtificially expanded genetic alphabet evolves enzymes for the first time
Libraries of short DNA sequences incorporating synthetic nucleotides perform better as enzymes than ordinary DNA
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FeatureThe brain chemicals that control what we enjoy
Researchers are trying to understand how orexins influence our appetites, and whether we can use them to treat addiction and obesity, explains Andy Extance
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OpinionWhy glycans?
Glycoscience is turning out to be more interesting than anyone might have imagined
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FeatureHow click conquered chemistry
Katrina Krämer tells the story of how click and bioorthogonal chemistry came to win the 2022 Nobel prize
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OpinionNobel vision
Looking beyond the here-and-now let click chemistry open up a whole new world of possibility
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OpinionCracking codons
Understanding how chemistry links RNA triplets to the properties of amino acids
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OpinionWhy AlphaFold won’t revolutionise drug discovery
Protein structure prediction is a hard problem, but even harder ones remain
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ResearchTeixobactin’s two pronged antibiotic attack mechanism revealed
Understanding of formation of deadly supramolecular structures could help build improved antimicrobials