Molecular biology – Page 7
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PodcastA Crack in Creation by Jennifer Doudna – Book club
The development of Crispr, and the ethical questions raised by new genome editing techniques
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FeatureCryo-EM: a cold, hard look at biology
Super cool microscopy wins the 2017 Nobel prize in chemistry
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NewsExplainer: What is cryo-electron microscopy
The science behind the 2017 Nobel prize in chemistry
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FeatureThe proteins of touch
Our sense of touch and balance is deeply ingrained in our experiences, but what are the chemical processes that make it work? Rachel Brazil investigates
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ResearchDNA helix has chiral water ‘spine’
Spectroscopy reveals how water molecules form a chiral superstructure in DNA’s minor groove
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OpinionUnpicking a clinical trial death
A new study shows up off-target effects of a drug that proved deadly, and highlights the pitfalls of drug discovery
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PodcastFibrin and fibrinogen
From scabby knees to life-threatening strokes, this important protein is the fundamental link in the complex molecular chain that forms blood clots
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PodcastPropranolol hydrochloride
Stave off stage fright with a simple compound that revolutionised drug development
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BusinessExpanding precision medicine beyond cancer
Exclusive interview with Koustubh Ranade, vice president of R&D at MedImmune
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ResearchReplication proteins send signals along DNA ‘wire’
DNA charge transport enables handover from one enzyme to another
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FeatureShedding light on the dark proteome
Around half of all human proteins are a mystery. What do they look like, asks Phil Ball
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OpinionPutting chemistry back in biology
The chemical nature of biomolecular interactions can no longer be ignored
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ResearchTumour cells' last breaths dampen down immune system
Dying cancer cells release potassium ions that alter the behaviour of T-cells
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ResearchSmallest ever genome gives life to minimal microbe
Stripped down bacterium has fewest genes of any replicating organism and will help scientists understand gene function
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NewsThe huge impact of ‘mini-brains’
‘Mini-brains’ created by Johns Hopkins researchers in the US could revolutionise how drugs and compounds are tested for safety and effectiveness
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NewsUse of Crispr on human embryos approved in UK
The UK’s fertility regulator will allow gene-edited human embryos to be used in research