All Neuroscience articles – Page 2
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BusinessSecond Alzheimer’s antibody approved in the US
Biogen–Eisai’s lecanemab can slow disease progression a little, but at significant cost and risk of side effects
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BusinessAlzheimer’s antibody engenders anticipation
Tantalising press-released data on Biogen and Eisai’s lecanemab prompt questions without firm answers
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OpinionAlzheimer’s, amyloid and abandoned antibodies
Biogen’s aducanumab is stumbling into obscurity. Where does that leave the amyloid hypothesis?
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FeatureThe curious case of the ancient brain
A 2000 year old decapitated Yorkshire man and the ancient proteins in his preserved brain might provide clues to modern diseases, as Hayley Bennett discovers
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OpinionWhen regulatory cooperation goes too far, we all lose
Were FDA staff unduly influenced by Biogen in approving Alzheimer’s antibody?
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BusinessAlzheimer’s antibody gets surprise US approval
Good news for industry and future drug approvals, but physicians doubt it will be effective for most patients
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ResearchBiochemical mystery unfolds as elemental metals found in Alzheimer’s patients’ brains
In a discovery that raises more question than it answers, researchers have found zero-oxidation-state iron and copper deposits inside amyloid plaques
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ReviewOn Task: How Our Brain Gets Things Done
From why brains are like search engine algorithms to tips on boosting your memory
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ResearchCase closed on decades old mystery of American bald eagle deaths
Invasive plant and cyanobacterium join up to form a deadly duo that have been killing US wildlife
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BusinessRegulatory panel unconvinced by Alzheimer’s antibody evidence
US FDA advisors vote against approving Biogen’s aducanumab on the basis of incomplete data analysis
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ResearchEngineered neurons synthesise their own conductive polymer coating
Cell-specific electric stimulation could help be used with bioelectronic prostheses or treat diseases like epilepsy
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Research‘Chemical ear defenders’ could prevent hearing loss
Discovery of receptor connected to hearing loss has led to a chemical compound that can protect the neuromechanical machinery in mice’s ears
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ResearchFour chemical classes cost US public 270 million IQ points over 15 years
Flame retardants and pesticides linked to over a million intellectual disability cases between 2001 and 2016
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ResearchSpectroscopic biomarkers track Huntington’s disease progression
Analysis recognises biochemical changes that are unique to Huntington’s
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NewsSwipe right to help in the fight against Huntington’s disease
Citizen science project improves understanding of protein misfolding disorders like Huntington’s and Alzheimer’s diseases
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ReviewExhibition: On Edge
Through artwork – videos, audio pieces, installations and paintings – this exhibition looks at how anxiety affects individuals and society.
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ResearchAlzheimer’s therapy has click chemistry use, then remove, brain copper build-ups
In situ drug synthesis catalysed by endogenous copper
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BusinessSixth in a line of Alzheimer’s drugs fails in trials
Treatments designed to stop amyloid peptide formation all seem to cause cognitive impairment rather than prevent it
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PodcastDomoic acid
The marine toxin that drives animals crazy and might have inspired one of Alfred Hitchcock’s most famous films