AI inspired by AlphaFold can predict chromatin structures found in chromosomes
System could help unravel how genome folding influences genes
An AI system can predict thousands of 3D structures of chromatin – the thread-like mixture of DNA and proteins that are packed into chromosomes – in just minutes. The deep learning approach could speed up research into how different chromatin structures affect the way genes are expressed in individual cells, important for understanding genetic diseases and developing gene-editing treatments.