App quantifies chemicals in thin layer chromatography

Researchers have developed a simple web app that converts thin layer chromatography (TLC) into a quantitative analytical technique. TLC separates compound mixtures on a sheet covered with an adsorbent material through the action of a solvent. One of the most basic analyses, chemists use TLC to monitor a reaction’s progress or quickly estimate a sample’s purity. There are also preparative versions that work like miniature chromatography columns. Students are often introduced to TLC by separating the components in black ink or identifying chemicals in leaf extracts.