All nucleophile articles
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ResearchOrigin of mysterious alpha effect in nucleophilic substitution reactions unveiled
Alpha nucleophiles’ ability to get close to electrophiles – rather than their intramolecular lone pair repulsion – gives them unusual reactivity
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ResearchAluminium shows unprecedented selectivity for breaking toughest bond
An aluminium complex reacts with tricyclic hydrocarbon’s most stable ring while ignoring easier-to-break carbon–carbon bonds
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ResearchChallenging mirror molecules made with stereochemistry destroying reaction
Clever catalyst repurposes classic nucleophilic substitution to make chiral quaternary carbon centres
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ResearchAnionic aluminium turns textbook knowledge on its head
First stable nucleophilic aluminium(I) compound offers new way to make aluminium–carbon bonds