Organic chemistry
The latest chemistry news and research on organic chemistry, including synthesis, natural products and total synthesis, reaction mechanisms and supramolecular chemistry, from the Royal Society of Chemistry's magazine, Chemistry World
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PodcastClick chemistry marks 25 years & covalent bonding in the actinides
Click chemistry: it’s in the name. How has this unique discipline made its mark over the last quarter decade? And, we discuss new experimental evidence of how covalent bonding works in the actinides.
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NewsSurprising oxidising power of carbon dioxide freed by photochemistry
Iron-based photocatalyst enabled a range of useful organic molecules to be synthesised from alkenes
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OpinionCelebrating click chemistry’s 25th birthday
The field ‘is nowhere near mature – if not in its infancy, then perhaps enjoying a highly active childhood’, says one of click chemistry’s orignators
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OpinionWhy I think it’s time to change how we teach the inductive effect
New evidence challenges the idea of long‑range inductive transmission, highlighting that some textbook explanations of inductive effects are oversimplified and, in key cases, completely wrong
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Research25 years ago click chemistry changed science. What happened next?
Barry Sharpless and his team first introduced the concept of ‘clicking’ molecules together 25 years ago
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OpinionClick chemistry, 25 years on
A quarter of a century since first introducing the concpet of ‘click’, one of its originators explains how it became a transformational tool for scientists
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ResearchStudy points to ammonia contamination in water microdroplets saga
Replication effort attributes mass spectrometry peaks to ammonium not hydroxyl species
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ResearchElusive electronic effect could explain the origins of chirality for all life on Earth
Study suggests spin selectivity is different in enantiomers – altering their reaction rate – which ‘challenges a fundamental assumption in the field’
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ResearchElectrifying MOF synthesis drastically reduces time it takes to make them
External electric fields stimulate the formation of various metal–organic framework materials
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Research‘Flip-over’ nucleophilic substitution reaction challenges classic SN2 textbook mechanism
Team behind work say this is a reminder that even simple reactions are more complicated than they first seem
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ResearchClick chemistry toolbox expanded with 'forbidden' C–C bond forming reaction
Copper-catalysed addition produces functional links that should be compatible with biological systems
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ResearchVersatile skeletal editing strategies upgrade nitrogen compounds into drug building blocks
Two techniques could help speed up the discovery of drugs containing nitrogen heterocycles
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ResearchSilver bullet catalyst works magic transforming stable C–H bonds into amines
Method allows for late-stage, stereoselective aminations to drug-like molecules
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ResearchMOF magnet with virtually no external magnetic field ideal for advanced electronics
Researchers say that the material could be used in spintronic devices
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ResearchFirst total synthesis of macrocycle with four stereocentres at the heart of bacterial photosynthesis
Technically daunting synthesis of bacteriochlorophyll a finally reaches completion
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Business‘Basic research is needed more than anything else’
Christian Hackenberger, co-founder of Tubulis, is excited that his team’s initial research is now creating clinical impact
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ResearchContra-thermodynamic stereochemical editing explained
How chemists are using light, enzymes and mechanical force to access higher‑energy stereoisomers without rebuilding a molecule from scratch
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ResearchUsing light to push stereochemistry uphill
While chemistry usually follows the downhill pull of thermodynamics, Alison Wendlandt is creating higher‑energy stereoisomers in the final stages of synthesis
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CareersSustainable laboratories: Cleaner solvents and substrates
How to identify greener replacements for DMF and recover ITO from glass substrates