Organic chemistry – Page 23
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ResearchSupramolecular mask simplifies fullerene modification
Porphyrin structure makes it easier to perform selective reactions on fullerene substrates
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ResearchFlow synthesis produces chiral intermediate for antidepressant drug
The first solvent-free organocatalytic flow process yields the key chiral intermediate for paroxetine on a multigram-scale
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FeatureSeparating turmeric fact from fiction
Thousands of papers have been published on curcumin’s healing potential, but its usefulness is not yet proven, finds Andy Extance
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PodcastBeta-damascenone
Louise Crane explains how a series of happy accidents led to the discovery of this rose-scented compound, found in rose oil, beer, apple pie and Kentucky bourbon.
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ResearchTotal synthesis of unnatural enantiomer renews interest in quinine
Scientists hope their strategy will invigorate cinchona alkaloid-mimic catalysis
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ResearchChemists taken aback as dinitrogen found to speed up some reactions
Warnings that nitrogen should no longer be considered just an inert carrier gas
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ResearchBiomimetic synthesis cultivates yellow poppy pigment
Cascade process that fuses indole with orientalin verifies biosynthesis of nudicaulins
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ResearchSteric shield leads boron to aromatic rings’ most remote region
Bulky blocking counterion makes quick work of borylating arenes’ inaccessible para position
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Opinion(±)-Rhabdastrellic acid A
A triterpene that looks innocuous until it reveals the highly strained conformation of its rings
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ResearchLight intensity changes can switch photocatalyst between one- and two-photon mechanisms
Simple optical lens behind strategy for manipulating photochemical reactivity
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ResearchLignin and carbon dioxide turned into ethanol
Process generates bulk chemical from two renewable carbon sources
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ResearchMystery of whether or not kekulene is superaromatic unravelled after 41 years
Second-ever synthesis and first atomic resolution images of superbenzene reveal its electronic nature
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PodcastCiguatoxin
The toxin found in reef fish that leads to food poisoning so bad it can cause life-long symptoms
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ResearchCarbynes expand the possibilities of carbon–carbon double bonds
Chemists use novel monovalent carbon species to insert functionalities in the middle of double bonds
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ResearchAlzheimer’s therapy has click chemistry use, then remove, brain copper build-ups
In situ drug synthesis catalysed by endogenous copper
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ResearchMetallohelices emulate antimicrobial peptides
Scientists move away from traditional drug candidates to evade resistance
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ResearchSynthetic flame retardant compounds turn up as marine natural products
Finding an alga that biosynthesises halogenated anilines increases likelihood of finding an organism that can degrade the toxic compounds too