Organic chemistry – Page 28
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Research
Supple sugars enable smallest cyclodextrins ever
Bridge that connects hydroxyls enables control over ring conformations in synthetic breakthrough
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Research
Polycyclic hydrocarbons finally make waves
New aromaticity insights could help advance organic electronics
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Research
Flexible catalyst systems open up nitrile chemistry
One new strategy enantioselectively produces amines from nitriles, and another generates valuable alkenyl nitriles
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News
Iupac names 10 chemistry innovations that will change the world
Nanopesticides, MOFs and 3D bioprinting among potential breakthrough technologies for a sustainable future
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Research
Ligand selector steers C–N cross-couplings down most sustainable path
Tool is step towards strategy that considers reagents and reactants above and below the arrow
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Research
Cobalt singled out for selective alcohol oxidation
Support network aids performance by isolating catalytic metal
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Research
New hydroamination reactions discovered after revisiting old mechanism
Unexpected but reasonable results show there’s nothing boring about organoboron chemistry
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Research
Warnings that dirty stirrer bars can act as phantom catalysts
Metal contaminants that can’t be removed by cleaning can be a serious problem for sensitive reactions
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Research
Co-crystals fish out cannabinoid from plant extract
Purifying cannabidiol from natural cannabis extract made cheap and easy thanks to amino acid partner
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Research
Can sodium make organic cross-couplings sustainable?
Microparticle dispersions make abundant but feisty sodium safer to use as replacements for organolithium in carbon–carbon bond formation
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Article
Creating carbon–carbon bonds via transition metal catalysis
Cross-coupling and metathesis reactions are powerful ways of making carbon–carbon bonds, the crucial links behind most organic compounds
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Podcast
Vinblastine and vincristine: Vinca alkaloids
Kat Arney unearths a story of an overlooked female researcher in the search for the origins of cancer drugs found in plants
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Opinion
What molecules should we make with a chemputer robot?
Digitising organic synthesis could revolutionise life in the lab
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Research
Synthesis-searching software’s superior scoring sharpens selections
Realistic costs and diverse suggestions make Chematica more insightful
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Research
16 benzene rings make up bulkiest ever acene
Largest perphenylacene behaves like tetracene in an inert hydrocarbon sheath
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Opinion
We’re going to need a bigger flask
Scaling up reactions is easy to get wrong in a variety of ways
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Research
The five reactions on every organic chemist’s wish list
Synthesis has some catching-up to do to create the reactions every drug discovery chemist dreams of