Organic chemistry – Page 31
-
ResearchObserving orbitals solves hydrogen transfer puzzle
Visualising atoms’ wave function lets chemists tell true from indirect hydrogen atom transfer
-
ResearchRed–blue light switch pushes equilibrium both ways
Switchable reaction cycle drives bond-making or breaking depending on light colour
-
ResearchStacked copper clusters create semiconducting supramolecule
Mixed valencies and overlapping π-electron clouds help electrons move from molecule to molecule
-
-
![Structural Characterization of r[5]C24+](https://d2cbg94ubxgsnp.cloudfront.net/Pictures/100x67/2/4/0/138240_CHEMPR499-10-7b.jpg)
ResearchMolecular necklace with record 24 positive charges made
Supercharged catenane squeezes 24 positive charges into five-ring interlocked system
-
ResearchRound-the-ring catalysis makes cyclic peptides chiral
Classic hydrogenation catalyst installs multiple stereocentres one by one to create small amino acid rings as single enantiomers
-
NewsMerck’s €10k synthesis competition will lab test routes
Pharma company offers €10,000 in prize money for retrosynthesis challenge that will bench test finalists’ proposals
-
FeatureDerek Barton and shape-shifting molecules
It’s 100 years since Derek Barton was born. Mike Sutton looks at his work developing conformational analysis
-
ResearchChameleon boron switches between electrophile and nucleophile
Mida boronates can be either electrophilic or nucleophilic in rearrangement reactions
-
-
ResearchHighly reactive carbocations tamed in bond forming reaction
Chemists harness vinyl cations for hydrocarbon synthesis and discover an unusual mechanism along the way
-
ResearchAntioxidant repair keeps radical reaction running
Repurposed antioxidant’s mechanism-mending properties make tough alkene alkylation possible
-
-
-
ResearchTextbook aromatic substitution mechanism overthrown
Established intermediate in nucleophilic aromatic substitution found to be a rare exception rather than the rule
-
ResearchNanotube locked inside a porphyrin
Rotaxane-like assembly formed from mechanically interlocked carbon nanotubes and macrocylic porphyrin rings
-
-
ResearchAI robot tests, predicts and even discovers reactions that are new to chemistry
Robotic chemist finds four unknown reactions and could speed up the discovery of new chemistry
-
Research‘Break it to make it’ reaction to diversify drugs structures
Carbon–carbon bond breaking reaction might make chemists rethink how they build molecules
-
ResearchMost complex reaction ever triggered by atomic manipulation makes molecular wire
Construction helps shed new light on mechanism of century-old reaction