Organic chemistry – Page 35
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ResearchMolecular box treats chemists to a strained surprise
Introducing pillar[4]pyridinium – the first of a new family of macrocycles
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ResearchSuper-reducing solvated electrons made with an LED
Laser-free method lowers the cost of producing hydrated electrons
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OpinionChanging the reproducibility rulebook
It pays to know when taking shortcuts is acceptable, and which it’s safe to take
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ResearchA light switch for chemical reactions
Different wavelengths of light can flip the route a reaction takes
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ResearchAI translates chemistry to predict reaction outcomes
Machine learning tool predicts products of organic reactions by treating chemistry like language
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ResearchTelescope arrangement puts a twist on organic synthesis
Solvents, move aside – scientists achieve dry multicomponent synthesis in a single step with twisting screws
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ResearchCalcium breaks ‘like repels like’ rule in benzene alkylation
Serendipitous discovery sees main-group metal topple textbook paradigm
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OpinionBeyond buckets and batches
Embracing flow chemistry means leaving behind some faithful friends
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ResearchOld and new spectroscopic techniques team up to decipher intricate alkaloids
Cutting-edge strategies set to increase our access to chemical space after researchers use them to verify unprecedented structures
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ResearchAcene synthesis sets new record for twisted molecules
Chemists prepare ‘twistacenes’ with torsion angles of up to 170º
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ResearchWhat’s left isn’t always right in total synthesis
Scientists turn detective to solve a decade-old stereochemical enigma
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ResearchTagging drugs with heavy hydrogen made as easy as flicking a light switch
Photoredox reaction simplifies metabolism studies by swapping hydrogen for deuterium or tritium
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OpinionThe value of quantification
A skills gap is emerging in organic synthesis that needs to be closed
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ResearchSpaces can be useful
Truly functional MOFs are on the horizon but Susumu Kitagawa saw their potential when they were weak and idle
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OpinionNatural selection
Bioactive compounds don’t just inspire new synthetic strategies, they’re also the ultimate test
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Opinion(‒)-Pavidolide B
An innovative approach to making five-membered carbon rings makes for a strikingly short synthesis
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ResearchFlash lithiation made safe
Micromixing enables protecting-group-free synthesis of organolithiums
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WebinarWho says there are no shortcuts to great chemistry?
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ResearchPurple crystals boast first aluminium double bond
Aluminium analogue of an alkene completes series of double-bonded boron group elements
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ResearchHelicene twists aromaticity to its limit
Six-pronged molecule contains the most twisted and least aromatic benzene ring found yet