Organic chemistry – Page 38
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Research
Algorithm modelled on Google’s AlphaGo beats chemists at their own game
Organic chemists prefer routes plotted by software to those of other chemists
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Opinion
Make room for randomness in drug development
Setting free the dark horses sometimes beats the most rational planning
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Webinar
Current topics in bioconjugation
Insights into making bioconjugates using optimal reagents and the latest techniques to create highly active and stable complexes
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Research
Electric shock brings diamines to life
A combination of electrochemistry and organic catalysis transforms alkenes into hard-to-make vicinal diamines
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Feature
Hofmann's chemistry factory
How two German chemists shaped chemistry education and research in Britain
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Research
Structural sleuthing salvages superbug slayer
Combining ‘assembly line’ synthesis, spectroscopy and computational predictions solves stereochemistry riddle
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Podcast
Piranha solution
When you need to get your glassware extremely clean, you need a cleaning solution with real ‘bite’
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Research
Unusual bicyclic molecule extends frontier of aromaticity
Odd resonance stabilisation observed in ground state opens door to studying poorly understood phenomenon
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Opinion
(+)-Pleuromutilin
Total synthesis is sometimes the only way to explore the chemical space around a natural product
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Research
Automated exploration of chemical space finds two new reactions
Synthetic chemists hit on undiscovered reactions by processing data from a high throughput screen of tens of thousands of potential products
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Research
Polar solvents promote halogen bonds over hydrogen ones
Solvent decides bonding battle winner in supramolecular systems
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Opinion
Nickel catalyst couples alcohols and carbon dioxide
Flexibility and low cost make nickel a firm favourite in catalysis
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Research
Giant ‘supersnowflakes’ start to lay
Self-assembled supramolecular structures overcome previous limitations
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Research
Protein cation is strongest organic acid ever made
Even inert gases fall prey to highly charged proteins
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