Pharmaceutical industry – Page 26
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FeatureEnvironmentally benign by design
The challenge of designing drugs with biodegradability in mind
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BusinessUS court denies Amgen appeal over Pfizer biosimilar
Amgen has lost its bid to compel Pfizer to divulge information about its version of anaemia drug Epogen
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BusinessRoche offloads majority of rights to lebrikizumab
Deal with Dermira could be worth well over $1 billion
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BusinessGSK stops over 30 research programmes to prioritise innovation
New boss Emma Walmsley outlines sweeping changes in order to focus on high-return drug projects
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BusinessAstraZeneca shares tumble after antibody failure
Imfinzi and tremelimumab checkpoint inhibitor pairing fails to beat chemotherapy in lung cancer
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BusinessNovartis coasts towards first CAR-T approval
Unanimous recommendation for CTL019 ahead of October decision builds confidence in T-cell genetic reprogramming
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Opinion(+)-Pleuromutilin
Total synthesis is sometimes the only way to explore the chemical space around a natural product
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BusinessBroad Institute backs central Crispr patent licensing platform
Key players submit 22 patents to pool, and urge other holders to create a one-stop shop for licensing deals
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BusinessLilly wins chemotherapy patent appeal
Firm also settles with generic manufacturers of erectile dysfunction drug Cialis
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BusinessMallinckrodt settles US opioid lawsuit
Firm will pay $35m over allegations it failed to report suspicious orders of controlled substances
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OpinionMaking enough of a difference
What if the needle in the drug development haystack ends up being too small to be useful?
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BusinessFDA approves first sickle cell drug in almost two decades
Glutamine-based drug is the first approved for children over 5
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BusinessCelgene and BeiGene agree cancer partnership
Immuno-oncology deal sees firms exchange licensing rights for antibody drugs
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BusinessSilence Therapeutics and Alnylam in patent dispute
Suit alleges competitors need to license Silence patents relating to their drug cantidates
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BusinessAmplifying intelligent drug design
This year’s Chemistry World Entrepreneur of the year is Andrew Hopkins of start-up Exscientia and the University of Dundee, UK
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ResearchLilly pushes continuous drug production limits
Integrated flow synthesis and purification process for prexasertib meets high industry standards
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BusinessFDA asks Endo to take pain drug off market
Request part of larger strategy to address opioid misuse in the US
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ArticleSygnature Discovery
Sygnature Discovery is part of an innovative partnership to bolster the life science sector in Nottingham
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BusinessJ&J licenses Protagonist’s inflammatory bowel peptide
Potential first-in-class treatment is just about to enter clinical trials
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OpinionUnpicking a clinical trial death
A new study shows up off-target effects of a drug that proved deadly, and highlights the pitfalls of drug discovery