All Reactions and synthesis articles – Page 13
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ResearchGlassware found to promote reactions in Miller–Urey 'primordial soup' experiment
By running their famous 1952 experiment in glass flasks, Stanley Miller and Harold Urey might have unintentionally simulated the role of rocks on early Earth
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ResearchAre organic chemists discovering fewer reactions than they were decades ago?
Analysis of millions of transformations reveals reliance on popular methods – and the rise of complex reactions
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ResearchPlasma-based approach leads to more reactive oxygen donors for alkene epoxidation
Yield of epoxidation reaction increased, and waste reduced, by using CO2-derived atomic oxygen and plasma-based conditions
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ResearchClippanes join rotaxanes and catenanes in mechanically interlocked molecule family
Keck-clip molecules consist of two entangled gold–carbene metallotweezers
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ResearchCooking oils work as solvents for metal-catalysed reactions
Suzuki–Miyaura, Hiyama, Stille, Sonogashira and Heck cross-couplings shown to proceed with quantitative yields in certain vegetable oils, fish oil, butter and waxes
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FeatureHow organocatalysis won the Nobel prize
Jamie Durrani tells the story of how two young upstarts, Ben List and David MacMillan, created a whole new field of catalysis
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ResearchExploiting evolution to explore chemical space shows promise for drug discovery
Using molecular trees – similar to family trees – chemists could predict how products will evolve to make new molecules
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ArticleAstraZeneca explores new frontiers through academic collaborations
The important of partnerships between industry and academia to drive innovation
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ResearchMöbius metallacycles show their aromaticity with textbook reactivity
First electrophilic aromatic substitution reactions with unusual molecules
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ResearchExplainer: why has asymmetric organocatalysis won the chemistry Nobel prize?
In a rather unexpected move by the Nobel committee, this year’s prize in chemistry has been awarded to Benjamin List and David MacMillan
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NewsAsymmetric organocatalysis scoops 2021 chemistry Nobel prize
Benjamin List and David MacMillan recognised for research that makes chemistry greener
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WebinarOptimising battery performance through materials characterisation
Discover how materials understanding is key to optimising the performance of battery technology and explore several key technologies to perform this characterisation
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ResearchPeptide superstructures speed up Michael reaction
A tripeptide that self-assembles into a supramolecular fibres accelerates an asymmetric benchmark reaction by up to 74%
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ResearchUltraphosphates break decades-old anti-branching rule
Discovery of elusive branched phosphates’ unexpected stability means they could have played a role in prebiotic chemistry
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ResearchMethod to make unusual oligonucleotides could be a boon for gene therapy drugs
Synthesis can insert unusual linkages into DNA molecules while rivalling industry standard chemistry in speed and efficiency
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ResearchEnantioselective synthesis of elusive chiral nitrogen compounds discovered by chance
An ‘elegant and simple’ way to make nitrogen stereocentres by supramolecular recognition
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ResearchElectrons in zinc’s filled 3d orbitals can participate in chemical reactions
Super electrophilic trianions accept three additional electrons to support zinc in a +3 oxidation state
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ResearchBlue light squeezes out heteroatoms from small rings
Photochemical ring editing reaction allows complete molecular shape change in a single step
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ResearchGold(III) catalysis transforms protecting group from base-stable to base-labile
Unique orthogonality in a protecting group achieved using a gold-catalysed cyclisation for selective activation and deprotection
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ResearchMolecular cryo-EM discovers error in 25-year-old natural product structure
Nobel prize-winning biomolecule imaging technique adapted to characterise chemical compounds faster and easier than NMR and x-ray