All Reactions and synthesis articles – Page 2
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ResearchComputer vision accelerates self-driving reaction workups from being automated to autonomous
Platform understands significance of solid residues, liquid levels, homogeneity, turbidity and colours
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OpinionExploring new fragments of chemical space
How medicinal and process chemists are working together to build better drugs
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ResearchFast flow-chemistry set-up facilitates sulfur-fluoride click chemistry
A modular method makes the most of flow-chemistry to create click-ready reagents selectively and efficiently
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ArticleChemistry needs the human element - here’s why
Automated R&D has huge potential, but we need to be kept in the loop
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FeatureCubanes help drugs take the strain
Medicinal chemists are increasingly exploring strained ring systems, George Barsted reports, believing they can serve as replacements for conventional building blocks in pharmaceuticals
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ResearchCarbon fibre plasma reactor enables extreme synthesis without compromise
Reactor can reach temperatures of 8000K without the need to choose between high temperatures or stability
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ResearchRobotic chemistry lab joins forces with Google AI to predict then make new inorganic materials
Algorithm discovered more than 2 million inorganic structures
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ResearchNew silicon-based protecting group removable with blue light
Benzoyldiisopropylchlorosilane protects primary, secondary and tertiary alcohols, and also works alongside other protecting groups
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NewsFuture House wants to build an AI biologist. They’re looking to a chemistry LLM for inspiration
ChemCrow has already recorded success researching, designing and producing an insecticide on its own
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ResearchSkeletal editing that simply swaps aromatic carbons for nitrogens will aid drug discovery
Atom-swapping chemistry gains two new techniques that are ready to use
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ResearchPlasma–microdroplet fusion enables catalyst-free amine alkylations
Microdroplet chemistry improves selectivity of plasma-mediated alkylation reactions
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OpinionSlow march of the retrosynthesis robots
Software synthesis suggestions are hampered by biased and incomplete datasets
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ResearchActivating a chemical reaction by ‘flipping a switch’
A low-cost microfluidic reactor could cut the environmental footprint of synthesis by directing electrons via an external electric field
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ResearchCarbon’s anti-aromatic allotrope is ringing the changes
The first synthesis of an anti-aromatic ring of pure carbon using atom manipulation
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ResearchUnexpected oscillations clarify mechanism of 100 year-old Fischer–Tropsch reaction
Discovery could pave the way to improved design of catalysts
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ResearchPlaying her part in building South Africa’s scientific reputation
Meet Pinkie Ntola, an early-career Black researcher who is passionate about being a credible scientist, an inspiring teacher and a supportive mentor
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ResearchSimple substitution creates subset of rhodamine fluorophores with extreme solubility
Tetramethyl-substituted 3-phosphonorhodamines look set to find use in cellular imaging
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ResearchLong-lived excited states open the door to earth-abundant metal photocatalysts
New findings show that cobalt (III) complexes can catalyse reactions not previously thought possible
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ResearchElectrophilic aromatic bromination study casts doubt on textbook intermediate
New computational evidence that electrophilic aromatic bromination actually occurs via an addition–elimination mechanism