All Reactions and synthesis articles – Page 3
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Feature
The quantum dot story
Julia Robinson explains how quantum dots went from a theoretical prediction to everyday reality and earned Alexei Ekimov, Louis Brus and Moungi Bawendi the 2023 Nobel prize in chemistry
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Research
Lasers and lithium team up for ammonia production at ambient conditions
A pioneering method uses lasers and lithium salts to fix nitrogen with record-breaking yields
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Webinar
Battery material changes in real-time: silicon anode structural evaluation via isothermal microcalorimetry
Learn about battery material changes and how to accelerate battery development using cutting-edge in-operando isothermal microcalorimetry
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Research
MOFs offer safer solution for handling fluorinated gases that can ‘tame the tiger’
Compounds vital in medicinal chemistry and imaging can be stored ready to use at room temperature
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Research
Doubly oxidised carbene tests the limits of the octet rule
Removal of two non-bonding electrons creates four-electron intermediate that could find use in synthesis
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Article
AstraZeneca strengthens academic collaborations for a sustainable future
Purpose-driven academic partnerships are helping AstraZeneca reduce its carbon footprint
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Research
Transformation analysis reveals structural similarities in FDA-approved drugs
Reaction informatics tools combined to create a new method for mapping chemical space
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Research
‘Transformative’ carbonyl cross-metathesis used to synthesise alkenes
Two new catalytic methods can produce a broad range of Z- and E-alkenes with remarkable cross-selectivity, paving the way for more efficient organic syntheses
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Research
Electrochemical conversion of acids to alkenes achieved on kilogram scale
Efficient production of valuable alkenes achieved under mild conditions by reversing hydrocarboxylation reaction
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Research
Chemical oscillator’s tick-tock action catalyses reaction regular as clockwork
Small molecule oscillator can catalyse Knoevenagel condensation periodically without affecting the oscillation
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Research
Organocatalyst deconstructs mixed plastic waste into monomers
Step towards closed-loop recycling
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Research
Clever ligand design enables alcohol-directed C-H activation
Despite being the most common functional group in nature alcohols have proven difficult to functionalise
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Research
Chemical industry hasn’t yet developed an appetite for biocatalysis, survey finds
Misconceptions along with a lack of time and resources driving industry’s reluctant attitude to biocatalysis and chemoenzymatic catalysis
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Research
Neural network boosts chiral ligand design
System trained on small dataset to optimise Negishi cross-coupling reaction
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Research
Hydrogen-free hydrogenation offers simple solution for medicinal chemists
New method expands electrochemical hydrogenation’s scope
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Research
ChatGPT predicts synthesis conditions for MOFs
Accessible AI tool can assess multitude of protocols for making new porous materials
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Research
Maillard reaction helps store carbon on the seafloor
Reaction that gives browned food its flavour could play crucial but underappreciated role in the ocean carbon cycle
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Research
Copper catalyst behind general strategy for synthesising methylenecyclobutane compounds
Simple method that produces strained and synthetically-demanding molecules could be a boon for medicinal chemists
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Research
Molecular cage seizes control in tetradehydro Diels–Alder reaction
Elegant method dodges harsh reaction conditions to assemble polycyclic scaffolds from simple linear precursors
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Research
86-year old Hammett equation gets a machine learning update
Algorithm opens the door to improved understanding of aromatic substituent effects