Structural biology – Page 3
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Research
Heavy metal proteins are the secret weapon in ant bites
Protein-rich biomaterials containing zinc, manganese, copper and bromine allow ants, crabs and scorpions to pack more punch for their size
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Research
Overreliance on cryocooled protein structures may compromise computational structure-based drug design
Scientists behind first of its kind study encourage more researchers to analyse protein structures at room temperature
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Feature
How a virus ancestor powers our memory’s chemistry
Andy Extance tells the astonishing story of the Arc protein and its capsid forms, and the questions it poses
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News
Machine learning delivers ‘human genome’ moment for proteins
Protein structure prediction tools AlphaFold and RoseTTAFold take the latest steps towards maturity and make their software open source
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Research
Enigmatic DNA dubbed ‘Borgs’ discovered in methane-metabolising microbes
The large nucleic acid structures may help bacteria play a role in regulating global methane
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Research
New class of biomolecule baffles scientists
GlycoRNAs found across several cell types and organisms
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Research
Redox switches up possibilities for signal transduction in artificial cells
Vitamin C triggers membrane translocation in a synthetic system, which generates an amplified fluorescent response
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News
Oxford University to open antimicrobial research centre after £100m donation from Ineos
Petrochemical giant highlights dangers of antibiotic resistance
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News
Decoding the virus – what we know about Sars-CoV-2 a year on
Scientists have never learnt so much about a pathogen in such a short time
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Research
Google’s AI aces protein prediction competition
Deep-learning network AlphaFold2’s perfomance at predicting how proteins fold has caused great excitement in the scientific community
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Feature
Artificial photosynthesis: solar water splitting
The chemistry to mimic ones of nature’s greatest feats still has some hurdles to overcome
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Feature
Artificial enzymes: catalysis by design
Enzymes are nature’s ultimate catalysts and chemists are now on the verge of making their own versions from scratch
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Research
Fruit flies’ protective corneal coatings reproduced
Anti-reflective and anti-adhesive nano-coating that covers the eyes of insects could find uses in medical implants and contact lenses
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Research
Viewpoint shift designs drug binding proteins from scratch
New method focuses on the groups touching amino acid side chains
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Opinion
Barbara Low, penicillin and the protein pi helix
Mike Sutton celebrates the remarkable career of a female crystallographer, once mistaken for the tea-lady
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Research
Decoding the chemistry behind cicada’s bacteria-killing wings
Organisation and composition of nanostructures help to explain unique properties
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Research
Unnatural cyclic amino acids push limits of ribosome
Expanding repertoire of monomers for ribosome-mediated polymerisation is boon for scientists wanting to harness nature’s protein factories
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Research
Photosynthesis rewired to generate hydrogen
Gene transplant repositions algal hydrogenase so that it directly captures electrons from photosystem I
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Research
Trapped enzyme reveals its unexpected shape-shifting ability
Metamorphic protein confined in nanopore found to switch between different 3D shapes as it catalyses a redox reaction
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News
Science steps up a gear as struggle to both understand and fight coronavirus intensifies
Research that might have taken years is being turned around in months as journals fast-track Covid-19 manuscripts