Synthetic biology and molecular machines – Page 3
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FeatureArtificial photosynthesis: solar water splitting
The chemistry to mimic ones of nature’s greatest feats still has some hurdles to overcome
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FeatureArtificial enzymes: catalysis by design
Enzymes are nature’s ultimate catalysts and chemists are now on the verge of making their own versions from scratch
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ResearchFruit flies’ protective corneal coatings reproduced
Anti-reflective and anti-adhesive nano-coating that covers the eyes of insects could find uses in medical implants and contact lenses
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ResearchSimple lipid networks combine self-assembly, replication, competition and inhibition
Artificial cells have previously lacked the complexity that is distinct to natural life but scientists are edging closer
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ResearchViewpoint shift designs drug binding proteins from scratch
New method focuses on the groups touching amino acid side chains
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OpinionEdgar Cahoon: ‘There is still so much basic knowledge to learn’
The biochemist and plant scientist talks about growing up on a dairy farm in Eastern Virginia, gardening, biking and Cornhusker football
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ResearchLight-harvesting wheel reinvented by chemists copying bacterium
Synthetic mimic of complex at the heart of photosynthesis offers new ways to capture solar energy
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ResearchUnnatural reaction benefits from computational tool that teaches an old enzyme new tricks
Method could generate artificial enzymes that are more suitable for directed evolution
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ResearchProtein synthesis revolution on way as large peptides made in hours not days
Flow chemistry can now make peptide chains up to 164 amino acids long in one go
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ResearchUnnatural cyclic amino acids push limits of ribosome
Expanding repertoire of monomers for ribosome-mediated polymerisation is boon for scientists wanting to harness nature’s protein factories
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ResearchPhotosynthesis rewired to generate hydrogen
Gene transplant repositions algal hydrogenase so that it directly captures electrons from photosystem I
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ResearchArtificial chloroplasts turn CO2 into multicarbon molecules, powered only by light
Microfluidic platform opens up non-natural metabolic pathways
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ResearchSoap-like catalyst outperforms enzyme with mimicry and micelles
Bioinspired approach could be used for a range of enzymes
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ResearchEngineered neurons synthesise their own conductive polymer coating
Cell-specific electric stimulation could help be used with bioelectronic prostheses or treat diseases like epilepsy
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ArticleTransforming innovation for startups
Green polymer specialists Novomer and biotech startup SynbiCite optimised industrial and biotech processes using design of experiment software from JMP
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ResearchFirst Crispr cancer trial in humans shows safety and durability
Immune-cell modifications target tumours and lift the PD-1 ‘brake’
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ResearchGiant, long-lived bacteria could make microbial farms more productive
Biochemical production could be boosted using Escherichia coli engineered to grow to 13 times their usual size
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ResearchBacterium forced to evolve to consume carbon dioxide to make biomass
Tweaked Escherichia coli could help deal with humanity’s carbon dioxide problem
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ResearchRobotic system can plan and perform biosynthesis without human intervention
New strategy combines machine learning with automation and has proven itself optimising a complex biochemical pathway