Synthetic biology and molecular machines – Page 4
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Research
First Crispr cancer trial in humans shows safety and durability
Immune-cell modifications target tumours and lift the PD-1 ‘brake’
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Research
Giant, long-lived bacteria could make microbial farms more productive
Biochemical production could be boosted using Escherichia coli engineered to grow to 13 times their usual size
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Research
Bacterium forced to evolve to consume carbon dioxide to make biomass
Tweaked Escherichia coli could help deal with humanity’s carbon dioxide problem
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Research
Robotic system can plan and perform biosynthesis without human intervention
New strategy combines machine learning with automation and has proven itself optimising a complex biochemical pathway
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Research
Engineered cyanobacteria turn carbon dioxide into petrol substitute
Strategy transforms wild photosynthetic organism into a system that could reduce humanity’s reliance on fossil fuels
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Research
Semi-synthetic bacteria make designer proteins
E. coli with synthetic DNA bases produce unnatural proteins that could be used as drugs
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Opinion
What happens when life has a limited vocabulary?
The longest synthetic genome shows us life is more complicated than just learning your AGCs
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Research
Enzyme evolved to selectively functionalise carbon–hydrogen bonds
Lactam libraries created by engineered bacterial enzyme offer new way to fight antibiotic resistance
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Research
First bacterium with a totally redesigned genome created
Designer E. coli uses a simplified genetic code to make proteins
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Research
Radical route produces non-natural polymers inside cells
Strategy could enable scientists to manipulate, track and control cellular behaviour by generating macromolecules within cells
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Research
Transcription controlled by non-natural DNA modifications
Proof-of-concept for artificial chemical epigenetics
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Research
Genetically engineered yeast brews up heady mix of natural and unnatural cannabinoids
Biotech yeast makes low-cost, high-quality THC and CBD – and cannabinoids never seen before – without growing cannabis plants
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Research
‘Predator particles’ give mice infrared vision
Upconversion nanoparticles that bind to rods and cones shift invisible light to look green
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News
Rogue Chinese scientist to be punished for creation of first gene-edited humans
Investigation uncovers forged ethical approval documents
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Opinion
Gene-editing put in the spotlight
What now after a rogue geneticist has created the first genetically modified humans?
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Research
Hidden gene cluster unearthed to reveal antibacterial natural product
Scientists encourage soil microorganisms to express themselves
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Research
Enzyme ancestors resurrected to boost thermal stability
Scientists constructing enzyme library make serendipitous discovery
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News
Pentagon’s pursuit of insect-delivered genetic modification of crops prompts warnings
French and German scientists worry that Darpa programme may violate the biological weapons convention and inadvertently start a new arms race
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Opinion
‘Chemists dismissed us as being too biologically focused’
How directed evolution winning the chemistry Nobel is going to change my field
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News
What is directed evolution and why did it win the chemistry Nobel prize?
If you’ve got questions about yesterday’s chemistry Nobel prize then we’ve got answers