Medicinal chemistry
The latest chemistry news and research on medicinal chemistry including drug discovery, clinical trials, toxicology and science of disease, from the Royal Society of Chemistry's magazine, Chemistry World
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BusinessPharmaceuticals roundup 2024
Diabetes and weight loss drugs have surged in popularity, revealing supply frailties
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ResearchmRNA therapy might one day treat deadly pre-eclampsia in pregnant women
Therapy helped pregnant mice to regrow placental blood vessels
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ResearchAI tool learns to build molecules fragment by fragment
Software tasked with designing a type-II kinase inhibitor suggests 97 candidates in 10 minutes, three of which were both synthesisable and effective at micromolar and nanomolar concentrations
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BusinessEurope reconsiders Alzheimer’s antibody approval
Leqembi recommended for approval with restrictions to reduce side effect risk
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ResearchFirst detected 40 years ago, a byproduct in chloraminated drinking water has finally been identified
Researchers call for urgent investigation into the chloronitramide anion’s toxicity
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OpinionDo chemists die young?
Death notices for chemists suggest perhaps not, despite the hazards found in many labs
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ResearchCyclopropyl effect causes substituents on cyclohexane to favour axial conformation
‘Unusual stereocontrol element’ will help medicinal chemists increase three-dimensionality of drug candidates
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ResearchA new gold standard in selective nitrobenzene hydrogenation
Reaction proceeds through a previously unidentified mechanism
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NewsmicroRNA discovery wins Nobel prize in medicine
Research on tiny RNA molecules unlocked mysteries of gene regulation and cell differentiation
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BusinessUS approves schizophrenia drug with new mode of action
Cobenfy promises to better address negative symptoms than existing antipsychotics
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WebinarEmerging routes to new therapeutics: Highlights from winning Horizon Prize teams
Discover how new therapeutics have the potential to address unmet medical needs
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WebinarThe science and promise of liquid biopsies: improving cancer treatment
Learn how liquid biopsies are being used to identify cancer and improve patient outcomes
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OpinionA chemist in the flower garden
The beautifully complex molecules plants produce are as inspiring as the blooms themselves
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FeatureBlood biopsies for cancer
Testing small amounts of blood for the presence of disease markers could revolutionise how we detect cancer. Clare Sansom reports
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ResearchYellow food dye could give doctors a new way to look beneath the skin
Tartrazine can safely and reversibly turn the skin of mice transparent
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BusinessTea tree oil faces ban in UK and EU over reprotoxicity
Defenders question relevance of animal safety data that triggered decision
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BusinessUS industry braced for change as election looms
Regulation, trade tariffs and innovation support top lists of concerns